Cycle Regulation in Islets with Diabetes Susceptibility A Gene Expression Network Model of Type 2 Diabetes Links Cell
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چکیده
Access the most recent version at doi: published online Mar 17, 2008; Genome Res. Alan D Attie Robert Kleinhanz, Scott Turner, Marc K Hellerstein, Eric E Schadt, Brian S Yandell, Christina Kendziorski and Stapleton, Carmen Argmann, Kathryn L Schueler, Seve Edwards, H Adam Steinberg, Elias Chaibub Neto, Mark P Keller, YounJeong Choi, Ping Wang, Dawn Belt Davis, Mary E Rabaglia, Angie T Oler, Donald S Cycle Regulation in Islets with Diabetes Susceptibility A Gene Expression Network Model of Type 2 Diabetes Links Cell
منابع مشابه
Gestational diabetes leads to down-regulation of CDK4-pRB-E2F1 pathway genes in pancreatic islets of rat offspring
Objective(s): The link between a hyperglycemic intrauterine environment and the development of diabetes later in life has been observed in offspring exposed to gestational diabetes mellitus (GDM), but the underlying mechanisms for this phenomenon are still not clear. Reduced β-cells mass is a determinant in the development of diabetes (type 1 and type 2 diabetes). Some recent studies have provi...
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Insulin resistance is necessary but not sufficient for the development of type 2 diabetes. Diabetes results when pancreatic beta-cells fail to compensate for insulin resistance by increasing insulin production through an expansion of beta-cell mass or increased insulin secretion. Communication between insulin target tissues and beta-cells may initiate this compensatory response. Correlated chan...
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The present study was conducted to test the effect of Origanum Majoranum Extract (OME) of leaves on alterations induced in a model of type 2 diabetic rats. Adult male Wistar rats were fed high fat diet for 3 weeks and injected a single dose of streptozotocin (35 mg/kg) intraperitoneally to induce type 2 diabetic rats. Diabetic rats were given aqueous extract of OME in a dose of 20 mg/kg orally ...
متن کاملOriganum Majoranum Extract Modulates Gene Expression, Hepatic and Renal Changes in a Rat Model of Type 2 Diabetes
The present study was conducted to test the effect of Origanum Majoranum Extract (OME) of leaves on alterations induced in a model of type 2 diabetic rats. Adult male Wistar rats were fed high fat diet for 3 weeks and injected a single dose of streptozotocin (35 mg/kg) intraperitoneally to induce type 2 diabetic rats. Diabetic rats were given aqueous extract of OME in a dose of 20 mg/kg orally ...
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